Symbol
Name
ID

Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
MGI:95413

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Decreased circulating IgG level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Abnormality of blood and blood-forming tissues

Anemia

Leukocytosis

Abnormal granulocyte morphology

Abnormal basophil morphology

Acute lymphoblastic leukemia

Ph-positive acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemias

Acute myeloid leukemia

Chronic myelogenous leukemia

Myeloproliferative disorder

Thrombocytopenia

Thrombocytosis

Lymphoma

Multiple myeloma

Myelodysplasia

Splenomegaly

Hepatosplenomegaly

Disease(s) Associated with ERCC2

acute lymphoblastic leukemia

acute myeloid leukemia

chronic myeloid leukemia

multiple myeloma

myelodysplastic syndrome

pancreatic cancer

photosensitive trichothiodystrophy 1

Mouse Phenotypes		hematopoietic system phenotype	enlarged spleen	anemia	decreased erythrocyte cell number	decreased hematocrit	abnormal hemoglobin	decreased hemoglobin content	microgliosis
Availability	Mouse Genotype	hematopoietic system phenotype	enlarged spleen	anemia	decreased erythrocyte cell number	decreased hematocrit	abnormal hemoglobin	decreased hemoglobin content	microgliosis
	Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^{tm2(ERCC2)Jhjh}
	Ercc2^tm3Jhjh/Ercc2^tm3Jhjh	*
	Ercc2^tm1Jhjh/Ercc2^{tm2(ERCC2)Jhjh}
	Ercc2^{tm2(ERCC2)Jhjh}/Ercc2^tm2Jmch

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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